The most common skin cancer and the most frequent cancer in humans, BCC affects more than 1 million people each year in the United States. BCC develops in the basal cells that make up the deepest layer of the epidermis, the top layer of the skin. It may appear as a shiny, translucent or pearly bump; a sore that does not heal; a pink, slightly elevated growth; a reddish irritated patch of skin; or a waxy scar-like lesion. It is most commonly found on skin that has been chronically exposed to the sun, such as the face, ears, scalp, chest, and back. Early diagnosis and treatment can prevent damage to surrounding tissue.